Fusion-Expressed CTB Improves Both Systemic and Mucosal T-Cell Responses Elicited by an Intranasal DNA Priming/Intramuscular Recombinant Vaccinia Boosting Regimen

Previous study showed that CTB (Cholera toxin subunit B) can be used as a genetic adjuvant to enhance the systemic immune responses. To further investigate whether it can also be used as a genetic adjuvant to improve mucosal immune responses, we constructed DNA and recombinant Tiantan vaccinia (rTTV...

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Autores principales: Qiu, Sugan, Ren, Xiaonan, Ben, Yinyin, Ren, Yanqin, Wang, Jing, Zhang, Xiaoyan, Wan, Yanmin, Xu, Jianqing
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988707/
https://ncbi.nlm.nih.gov/pubmed/24741585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/308732
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