Rapid Anxiolytic Effects of a 5-HT(4) Receptor Agonist Are Mediated by a Neurogenesis-Independent Mechanism

Selective serotonin reuptake inhibitors (SSRIs) display a delayed onset of action of several weeks. Past work in naive rats showed that 5-HT(4) receptor agonists had rapid effects on depression-related behaviors and on hippocampal neurogenesis. We decided to investigate whether 5-HT(4) receptor stim...

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Detalhes bibliográficos
Main Authors: Mendez-David, Indira, David, Denis J, Darcet, Flavie, Wu, Melody V, Kerdine-Römer, Saadia, Gardier, Alain M, Hen, René
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988540/
https://ncbi.nlm.nih.gov/pubmed/24287720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.332
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