Evidence for a Role of Transporter-Mediated Currents in the Depletion of Brain Serotonin Induced by Serotonin Transporter Substrates

Serotonin (5-HT) transporter (SERT) substrates like fenfluramine and 3,4-methylenedioxymethamphetamine cause long-term depletion of brain 5-HT, while certain other substrates do not. The 5-HT deficits produced by SERT substrates are dependent upon transporter proteins, but the exact mechanisms respo...

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Detalhes bibliográficos
Main Authors: Baumann, Michael H, Bulling, Simon, Benaderet, Tova S, Saha, Kusumika, Ayestas, Mario A, Partilla, John S, Ali, Syed F, Stockner, Thomas, Rothman, Richard B, Sandtner, Walter, Sitte, Harald H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988539/
https://ncbi.nlm.nih.gov/pubmed/24287719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.331
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