Low Protein Intake is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population

Mice and humans with Growth Hormone Receptor/IGF-1 deficiencies display major reductions in age-related diseases. Because protein restriction reduces GHR-IGF-1 activity, we examined links between protein intake and mortality. Respondents (n=6,381) aged 50–65 reporting high protein intake had a 75% i...

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Detalhes bibliográficos
Main Authors: Levine, Morgan E., Suarez, Jorge A., Brandhorst, Sebastian, Balasubramanian, Priya, Cheng, Chia-Wei, Madia, Federica, Fontana, Luigi, Mirisola, Mario G., Guevara-Aguirre, Jaime, Wan, Junxiang, Passarino, Giuseppe, Kennedy, Brian K., Cohen, Pinchas, Crimmins, Eileen M., Longo, Valter D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988204/
https://ncbi.nlm.nih.gov/pubmed/24606898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.02.006
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