KCTD1 Suppresses Canonical Wnt Signaling Pathway by Enhancing β-catenin Degradation

The canonical Wnt signaling pathway controls normal embryonic development, cellular proliferation and growth, and its aberrant activity results in human carcinogenesis. The core component in regulation of this pathway is β-catenin, but molecular regulation mechanisms of β-catenin stability are not c...

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Bibliographische Detailangaben
Hauptverfasser: Li, Xinxin, Chen, Cheng, Wang, Fangmei, Huang, Wenhuan, Liang, Zhongheng, Xiao, Yuzhong, Wei, Ke, Wan, Zhenxing, Hu, Xiang, Xiang, Shuanglin, Ding, Xiaofeng, Zhang, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988066/
https://ncbi.nlm.nih.gov/pubmed/24736394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094343
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