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KCTD1 Suppresses Canonical Wnt Signaling Pathway by Enhancing β-catenin Degradation
The canonical Wnt signaling pathway controls normal embryonic development, cellular proliferation and growth, and its aberrant activity results in human carcinogenesis. The core component in regulation of this pathway is β-catenin, but molecular regulation mechanisms of β-catenin stability are not c...
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Κύριοι συγγραφείς: | , , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Public Library of Science
2014
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3988066/ https://ncbi.nlm.nih.gov/pubmed/24736394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094343 |
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