KCTD1 Suppresses Canonical Wnt Signaling Pathway by Enhancing β-catenin Degradation

The canonical Wnt signaling pathway controls normal embryonic development, cellular proliferation and growth, and its aberrant activity results in human carcinogenesis. The core component in regulation of this pathway is β-catenin, but molecular regulation mechanisms of β-catenin stability are not c...

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Detalhes bibliográficos
Main Authors: Li, Xinxin, Chen, Cheng, Wang, Fangmei, Huang, Wenhuan, Liang, Zhongheng, Xiao, Yuzhong, Wei, Ke, Wan, Zhenxing, Hu, Xiang, Xiang, Shuanglin, Ding, Xiaofeng, Zhang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988066/
https://ncbi.nlm.nih.gov/pubmed/24736394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094343
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