The Early Activation of Toll-Like Receptor (TLR)-3 Initiates Kidney Injury after Ischemia and Reperfusion

Acute kidney injury (AKI) is one of the most important complications in hospitalized patients and its pathomechanisms are not completely elucidated. We hypothesize that signaling via toll-like receptor (TLR)-3, a receptor that is activated upon binding of double-stranded nucleotides, might play a cr...

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Detalhes bibliográficos
Main Authors: Paulus, Patrick, Rupprecht, Katrin, Baer, Patrick, Obermüller, Nicholas, Penzkofer, Daniela, Reissig, Christin, Scheller, Bertram, Holfeld, Johannes, Zacharowski, Kai, Dimmeler, Stefanie, Schlammes, Joelle, Urbschat, Anja
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988056/
https://ncbi.nlm.nih.gov/pubmed/24736450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094366
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