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The Small Fibrinopeptide Bβ(15–42) as Renoprotective Agent Preserving the Endothelial and Vascular Integrity in Early Ischemia Reperfusion Injury in the Mouse Kidney

Disruption of the renal endothelial integrity is pivotal for the development of a vascular leak, tissue edema and consequently acute kidney injury. Kidney ischemia amplifies endothelial activation and up-regulation of pro-inflammatory mechanisms. After restoring a sufficient blood flow, the kidney i...

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Autors principals: Urbschat, Anja, Zacharowski, Kai, Obermüller, Nicholas, Rupprecht, Katrin, Penzkofer, Daniela, Jennewein, Carla, Tran, Nguyen, Scheller, Bertram, Dimmeler, Stefanie, Paulus, Patrick
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879329/
https://ncbi.nlm.nih.gov/pubmed/24392138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084432
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