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Hyaluronic acid hydrogel stiffness and oxygen tension affect cancer cell fate and endothelial sprouting

Three-dimensional (3D) tissue culture models may recapitulate aspects of the tumorigenic microenvironment in vivo, enabling the study of cancer progression in vitro. Both hypoxia and matrix stiffness are known to regulate tumor growth. Using a modular culture system employing an acrylated hyaluronic...

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Sonraí Bibleagrafaíochta
Main Authors: Shen, Yu-I, Abaci, Hasan E., Krupsi, Yoni, Weng, Lien-Chun, Burdick, Jason A., Gerecht, Sharon
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987918/
https://ncbi.nlm.nih.gov/pubmed/24748963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3BM60274E
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