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Human polyoma JC virus minor capsid proteins, VP2 and VP3, enhance large T antigen binding to the origin of viral DNA replication: Evidence for their involvement in regulation of the viral DNA replication

JC virus (JCV) lytically infects the oligodendrocytes in the central nervous system in a subset of immunocompromized patients and causes the demyelinating disease, progressive multifocal leukoencephalopathy. JCV replicates and assembles into infectious virions in the nucleus. However, understanding...

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Autors principals: Saribas, A. Sami, Mun, Sarah, Johnson, Jaslyn, El-Hajmoussa, Mohammad, White, Martyn K., Safak, Mahmut
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987903/
https://ncbi.nlm.nih.gov/pubmed/24418532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.10.031
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