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Accelerated recovery of renal mitochondrial and tubule homeostasis with SIRT1/PGC-1α activation following ischemia-reperfusion injury

Kidney ischemia-reperfusion (I/R) injury elicits cellular injury in the proximal tubule, and mitochondrial dysfunction is a pathological consequence of I/R. Promoting mitochondrial biogenesis (MB) as a repair mechanism after injury may offer a unique strategy to restore both mitochondrial and organ...

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Hlavní autoři: Funk, Jason A., Schnellmann, Rick G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987743/
https://ncbi.nlm.nih.gov/pubmed/24096033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.09.026
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