SRT1720 Induces Mitochondrial Biogenesis and Rescues Mitochondrial Function after Oxidant Injury in Renal Proximal Tubule Cells

Mitochondrial biogenesis occurs under basal conditions and is an adaptive response initiated by cells to maintain energetic demands and metabolic homeostasis after injuries targeting mitochondrial function. Identifying pharmacological agents that stimulate mitochondrial biogenesis is a critical step...

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Detalhes bibliográficos
Main Authors: Funk, Jason A., Odejinmi, Sina, Schnellmann, Rick G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Gastrointestinal, Hepatic, Pulmonary, and Renal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872958/
https://ncbi.nlm.nih.gov/pubmed/20103585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.161992
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