SRT1720 Induces Mitochondrial Biogenesis and Rescues Mitochondrial Function after Oxidant Injury in Renal Proximal Tubule Cells

Mitochondrial biogenesis occurs under basal conditions and is an adaptive response initiated by cells to maintain energetic demands and metabolic homeostasis after injuries targeting mitochondrial function. Identifying pharmacological agents that stimulate mitochondrial biogenesis is a critical step...

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Hlavní autoři: Funk, Jason A., Odejinmi, Sina, Schnellmann, Rick G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2010
Témata:
Gastrointestinal, Hepatic, Pulmonary, and Renal
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872958/
https://ncbi.nlm.nih.gov/pubmed/20103585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.161992
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