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SRT1720 Induces Mitochondrial Biogenesis and Rescues Mitochondrial Function after Oxidant Injury in Renal Proximal Tubule Cells

Mitochondrial biogenesis occurs under basal conditions and is an adaptive response initiated by cells to maintain energetic demands and metabolic homeostasis after injuries targeting mitochondrial function. Identifying pharmacological agents that stimulate mitochondrial biogenesis is a critical step...

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Autors principals: Funk, Jason A., Odejinmi, Sina, Schnellmann, Rick G.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872958/
https://ncbi.nlm.nih.gov/pubmed/20103585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.161992
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