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Transcriptional override: a regulatory network model of indirect responses to modulations in microRNA expression

BACKGROUND: Documented changes in levels of microRNAs (miRNA) in a variety of diseases including cancer are leading to their development as early indicators of disease, and as a potential new class of therapeutic agents. A significant hurdle to the rational application of miRNAs as therapeutics is o...

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Détails bibliographiques
Auteurs principaux: Hill, Christopher G, Matyunina, Lilya V, Walker, DeEtte, Benigno, Benedict B, McDonald, John F
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987680/
https://ncbi.nlm.nih.gov/pubmed/24666724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-36
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