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Recent advances in the treatment of gastrointestinal stromal tumors

Constitutively activating mutations in the KIT and platelet-derived growth factor receptor α (PDGFRA) RTKs play a crucial role in the biology of gastrointestinal stromal tumors (GISTs), and this disease has served as an effective model for targeting gain-of-function kinase mutations in cancer. Imati...

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Dettagli Bibliografici
Autori principali: Serrano, César, George, Suzanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987653/
https://ncbi.nlm.nih.gov/pubmed/24790651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834014522491
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