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Recent advances in managing gastrointestinal stromal tumor

Constitutive activating mutations in KIT and platelet-derived growth factor receptor α ( PDGFRα) are heavily involved in the pathobiology of gastrointestinal stromal tumors (GISTs). This disease has served as an effective “proof-of-concept” model for targeting gain-of-function kinase mutations in ca...

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書目詳細資料
發表在:F1000Res
Main Authors: Duffaud, Florence, Le Cesne, Axel
格式: Artigo
語言:Inglês
出版: F1000Research 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600003/
https://ncbi.nlm.nih.gov/pubmed/28928967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.11118.1
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