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Recent advances in the treatment of gastrointestinal stromal tumors
Constitutively activating mutations in the KIT and platelet-derived growth factor receptor α (PDGFRA) RTKs play a crucial role in the biology of gastrointestinal stromal tumors (GISTs), and this disease has served as an effective model for targeting gain-of-function kinase mutations in cancer. Imati...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
SAGE Publications
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3987653/ https://ncbi.nlm.nih.gov/pubmed/24790651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834014522491 |
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