Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences.

RNA editing by adenosine deamination in brain-expressed pre-mRNAs for glutamate receptor (GluR) subunits alters gene-specified codons for functionally critical positions, such as the channel's Q/R site. We show by transcript analysis of minigenes transiently expressed in PC-12 cells that, in contras...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Herb, A, Higuchi, M, Sprengel, R, Seeburg, P H
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39875/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700852/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.1875
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