A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells

How adherent and contractile systems coordinate to promote cell shape changes is unclear. Here, we define a counterbalanced adhesion/contraction model for cell shape control. Live-cell microscopy data showed a crucial role for a contractile meshwork at the top of the cell, which is composed of actin...

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Detalhes bibliográficos
Main Authors: Burnette, Dylan T., Shao, Lin, Ott, Carolyn, Pasapera, Ana M., Fischer, Robert S., Baird, Michelle A., Der Loughian, Christelle, Delanoe-Ayari, Helene, Paszek, Matthew J., Davidson, Michael W., Betzig, Eric, Lippincott-Schwartz, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987145/
https://ncbi.nlm.nih.gov/pubmed/24711500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201311104
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