Neurofilament Heavy polypeptide CpG island methylation associates with prognosis of renal cell carcinoma and prediction of antivascular endothelial growth factor therapy response

Neurofilament Heavy polypeptid (NEFH) belongs to the group of type IV intermediate filament proteins. DNA methylation of the NEFH promoter and loss of expression have previously been shown to activate the AKT/β-catenin pathway in tumor cells. When identifying hypermethylation of the NEFH CpG island...

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Detalhes bibliográficos
Main Authors: Dubrowinskaja, Natalia, Gebauer, Kai, Peters, Inga, Hennenlotter, Jörg, Abbas, Mahmoud, Scherer, Ralph, Tezval, Hossein, Merseburger, Axel S, Stenzl, Arnulf, Grünwald, Viktor, Kuczyk, Markus A, Serth, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons Ltd 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987080/
https://ncbi.nlm.nih.gov/pubmed/24464810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.181
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