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The effects of nonspecific HIF1α inhibitors on development of castrate resistance and metastases in prostate cancer

Expression of hypoxia-inducible factor (HIF)1α increases the risk of castrate-resistant prostate cancer (CRPC) and metastases in patients on androgen deprivation therapy (ADT) for prostate cancer (PC). We aimed to investigate the effects of nonspecific HIF1α inhibitors (Digoxin, metformin, and angio...

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Detalhes bibliográficos
Main Authors: Ranasinghe, Weranja K B, Sengupta, Shomik, Williams, Scott, Chang, Mike, Shulkes, Arthur, Bolton, Damien M, Baldwin, Graham, Patel, Oneel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987074/
https://ncbi.nlm.nih.gov/pubmed/24464861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.189
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