The Role of Hypoxia-Inducible Factor 1α in Determining the Properties of Castrate-Resistant Prostate Cancers

BACKGROUND: Castrate-resistant prostate cancer (CRPC) is a lethal condition in patients receiving androgen deprivation therapy for prostate cancer (PC). Despite numerous studies showing the expression of HIF1α protein under normoxia in PC cell lines, the role of this normoxic HIF1α expression in che...

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Detalhes bibliográficos
Main Authors: Ranasinghe, Weranja K. B., Xiao, Lin, Kovac, Suzana, Chang, Mike, Michiels, Carine, Bolton, Damien, Shulkes, Arthur, Baldwin, Graham S., Patel, Oneel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546972/
https://ncbi.nlm.nih.gov/pubmed/23342109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054251
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