Miglitol increases energy expenditure by upregulating uncoupling protein 1 of brown adipose tissue and reduces obesity in dietary-induced obese mice

BACKGROUND: Miglitol is an oral anti-diabetic drug that acts by inhibiting carbohydrate absorption in the small intestine. Recent studies have shown that miglitol reduces obesity in humans and rodents. However, its mechanisms have remained unclear. The purpose of this study was to determine whether...

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Main Authors: Sugimoto, Satoru, Nakajima, Hisakazu, Kodo, Kazuki, Mori, Jun, Matsuo, Kensuke, Kosaka, Kitaro, Aoi, Wataru, Yoshimoto, Kanji, Ikegaya, Hiroshi, Hosoi, Hajime
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986880/
https://ncbi.nlm.nih.gov/pubmed/24669882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-11-14
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