High-fat diet accelerates extreme obesity with hyperphagia in female heterozygous Mecp2-null mice

Rett syndrome (RTT) is an X-linked neurodevelopmental disorder caused by mutation of the methyl-CpG-binding protein 2 (MECP2) gene. Although RTT has been associated with obesity, the underlying mechanism has not yet been elucidated. In this study, female heterozygous Mecp2-null mice (Mecp2(+/-) mice...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fukuhara, Shota, Nakajima, Hisakazu, Sugimoto, Satoru, Kodo, Kazuki, Shigehara, Keiichi, Morimoto, Hidechika, Tsuma, Yusuke, Moroto, Masaharu, Mori, Jun, Kosaka, Kitaro, Morimoto, Masafumi, Hosoi, Hajime
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319720/
https://ncbi.nlm.nih.gov/pubmed/30608967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210184
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