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FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice
Steroidogenic factor 1 (SF1; Ad4BP/NR5A1) plays key roles in gonadal development. Initially, the Sf1 gene is expressed in mouse fetal gonads of both sexes, but later is up-regulated in testes and down-regulated in ovaries. While Sf1 expression is activated and maintained by Wilms tumor 1 (WT1) and L...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Federation of American Societies for Experimental Biology
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986836/ https://ncbi.nlm.nih.gov/pubmed/24451388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-246108 |
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