Загрузка...

JNK confers 5-fluorouracil resistance in p53-deficient and mutant p53-expressing colon cancer cells by inducing survival autophagy

Deficiency or mutation in the p53 tumor suppressor gene commonly occurs in human cancer and can contribute to disease progression and chemotherapy resistance. Currently, although the pro-survival or pro-death effect of autophagy remains a controversial issue, increasing data seem to support the idea...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Sui, Xinbing, Kong, Na, Wang, Xian, Fang, Yong, Hu, Xiaotong, Xu, Yinghua, Chen, Wei, Wang, Kaifeng, Li, Da, Jin, Wei, Lou, Fang, Zheng, Yu, Hu, Hong, Gong, Liu, Zhou, Xiaoyun, Pan, Hongming, Han, Weidong
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986705/
https://ncbi.nlm.nih.gov/pubmed/24733045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04694
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!