JNK confers 5-fluorouracil resistance in p53-deficient and mutant p53-expressing colon cancer cells by inducing survival autophagy

Deficiency or mutation in the p53 tumor suppressor gene commonly occurs in human cancer and can contribute to disease progression and chemotherapy resistance. Currently, although the pro-survival or pro-death effect of autophagy remains a controversial issue, increasing data seem to support the idea...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sui, Xinbing, Kong, Na, Wang, Xian, Fang, Yong, Hu, Xiaotong, Xu, Yinghua, Chen, Wei, Wang, Kaifeng, Li, Da, Jin, Wei, Lou, Fang, Zheng, Yu, Hu, Hong, Gong, Liu, Zhou, Xiaoyun, Pan, Hongming, Han, Weidong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986705/
https://ncbi.nlm.nih.gov/pubmed/24733045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04694
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