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Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes
Heme (iron-protoporphyrin IX) is an essential co-factor involved in multiple biological processes: oxygen transport and storage, electron transfer, drug and steroid metabolism, signal transduction, and micro RNA processing. However, excess free-heme is highly toxic due to its ability to promote oxid...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986552/ https://ncbi.nlm.nih.gov/pubmed/24782769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00061 |
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