Right ventricular dysfunction in the R6/2 transgenic mouse model of Huntington’s disease is unmasked by dobutamine

BACKGROUND: Increasingly, evidence from studies in both animal models and patients suggests that cardiovascular dysfunction is important in HD. Previous studies measuring function of the left ventricle (LV) in the R6/2 model have found a clear cardiac abnormality, albeit with preserved LV systolic f...

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Main Authors: Buonincontri, Guido, Wood, Nigel I., Puttick, Simon G., Ward, Alex O., Carpenter, T. Adrian, Sawiak, Stephen J., Morton, A. Jennifer
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986496/
https://ncbi.nlm.nih.gov/pubmed/24744818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-130083
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