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Direct evidence of progressive cardiac dysfunction in a transgenic mouse model of Huntington’s disease

The gene carrying the mutation causing Huntington’s disease (HD) is not brain specific, and there is increasing evidence for peripheral, as well as brain pathology in this disorder. Here, we used in vivo and ex vivo techniques to assess the cardiac function of mice transgenic for the HD mutation. Us...

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Detalhes bibliográficos
Main Authors: Wood, Nigel I., Sawiak, Stephen J., Buonincontri, Guido, Niu, Youguo, Kane, Andrew D., Carpenter, T. Adrian, Giussani, Dino A., Morton, A. Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856869/
https://ncbi.nlm.nih.gov/pubmed/24339845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-2012-120004
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