Direct evidence of progressive cardiac dysfunction in a transgenic mouse model of Huntington’s disease

The gene carrying the mutation causing Huntington’s disease (HD) is not brain specific, and there is increasing evidence for peripheral, as well as brain pathology in this disorder. Here, we used in vivo and ex vivo techniques to assess the cardiac function of mice transgenic for the HD mutation. Us...

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Bibliographic Details
Main Authors: Wood, Nigel I., Sawiak, Stephen J., Buonincontri, Guido, Niu, Youguo, Kane, Andrew D., Carpenter, T. Adrian, Giussani, Dino A., Morton, A. Jennifer
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856869/
https://ncbi.nlm.nih.gov/pubmed/24339845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-2012-120004
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