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Staphylococcus aureus Alpha-Toxin Mediates General and Cell Type-Specific Changes in Metabolite Concentrations of Immortalized Human Airway Epithelial Cells

Staphylococcus aureus alpha-toxin (Hla) is a potent pore-forming cytotoxin that plays an important role in the pathogenesis of S. aureus infections, including pneumonia. The impact of Hla on the dynamics of the metabolome in eukaryotic host cells has not been investigated comprehensively. Using (1)H...

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Autors principals: Gierok, Philipp, Harms, Manuela, Richter, Erik, Hildebrandt, Jan-Peter, Lalk, Michael, Mostertz, Jörg, Hochgräfe, Falko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986243/
https://ncbi.nlm.nih.gov/pubmed/24733556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094818
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