Mycobactericidal Activity of Sutezolid (PNU-100480) in Sputum (EBA) and Blood (WBA) of Patients with Pulmonary Tuberculosis

RATIONALE: Sutezolid (PNU-100480) is a linezolid analog with superior bactericidal activity against Mycobacterium tuberculosis in the hollow fiber, whole blood and mouse models. Like linezolid, it is unaffected by mutations conferring resistance to standard TB drugs. This study of sutezolid is its f...

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Detalhes bibliográficos
Main Authors: Wallis, Robert S., Dawson, Rodney, Friedrich, Sven O., Venter, Amour, Paige, Darcy, Zhu, Tong, Silvia, Annette, Gobey, Jason, Ellery, Craig, Zhang, Yao, Eisenach, Kathleen, Miller, Paul, Diacon, Andreas H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986205/
https://ncbi.nlm.nih.gov/pubmed/24732289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094462
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