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Retinoid X receptor-selective ligands produce malformations in Xenopus embryos.

Retinoids exert pleiotropic effects on the development of vertebrates through the action of retinoic acid receptors (RAR) and retinoid X receptors (RXR). We have investigated the effect of synthetic retinoids selective for RXR and RAR on the development of Xenopus and zebrafish embryos. In Xenopus,...

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Bibliographic Details
Main Authors: Minucci, S, Saint-Jeannet, J P, Toyama, R, Scita, G, DeLuca, L M, Tiara, M, Levin, A A, Ozato, K, Dawid, I B
Format: Artigo
Language:Inglês
Published: 1996
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC39862/
https://ncbi.nlm.nih.gov/pubmed/8700839
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