Extended lifespan and reduced adiposity in mice lacking the FAT10 gene

The HLA-F adjacent transcript 10 (FAT10) is a member of the ubiquitin-like gene family that alters protein function/stability through covalent ligation. Although FAT10 is induced by inflammatory mediators and implicated in immunity, the physiological functions of FAT10 are poorly defined. We report...

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Hlavní autoři: Canaan, Allon, DeFuria, Jason, Perelman, Eddie, Schultz, Vincent, Seay, Montrell, Tuck, David, Flavell, Richard A., Snyder, Michael P., Obin, Martin S., Weissman, Sherman M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986194/
https://ncbi.nlm.nih.gov/pubmed/24706839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323426111
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