Pharmacological inhibition of the chemokine receptor CX3CR1 attenuates disease in a chronic-relapsing rat model for multiple sclerosis

One hallmark of multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE) is infiltration of leukocytes into the CNS, where chemokines and their receptors play a major mediatory role. CX3CR1 is a chemokine receptor involved in leukocyte adhesion and migration and hence a mediator o...

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Main Authors: Ridderstad Wollberg, Anna, Ericsson-Dahlstrand, Anders, Juréus, Anders, Ekerot, Petra, Simon, Sylvia, Nilsson, Maria, Wiklund, Stig-Johan, Berg, Anna-Lena, Ferm, Mats, Sunnemark, Dan, Johansson, Rolf
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2014
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986185/
https://ncbi.nlm.nih.gov/pubmed/24706865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316510111
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