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Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE

BACKGROUND: The CC chemokine receptors CCR1, CCR2 and CCR5 are critical for the recruitment of mononuclear phagocytes to the central nervous system (CNS) in multiple sclerosis (MS) and other neuroinflammatory diseases. Mononuclear phagocytes are effector cells capable of phagocytosing myelin and dam...

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Detalhes bibliográficos
Main Authors: Eltayeb, Sana, Berg, Anna-Lena, Lassmann, Hans, Wallström, Erik, Nilsson, Maria, Olsson, Tomas, Ericsson-Dahlstrand, Anders, Sunnemark, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884136/
https://ncbi.nlm.nih.gov/pubmed/17484785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-4-14
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