Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE

BACKGROUND: The CC chemokine receptors CCR1, CCR2 and CCR5 are critical for the recruitment of mononuclear phagocytes to the central nervous system (CNS) in multiple sclerosis (MS) and other neuroinflammatory diseases. Mononuclear phagocytes are effector cells capable of phagocytosing myelin and dam...

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Hauptverfasser: Eltayeb, Sana, Berg, Anna-Lena, Lassmann, Hans, Wallström, Erik, Nilsson, Maria, Olsson, Tomas, Ericsson-Dahlstrand, Anders, Sunnemark, Dan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884136/
https://ncbi.nlm.nih.gov/pubmed/17484785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-4-14
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