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T cells down-regulate macrophage TNF production by IRAK1-mediated IL-10 expression and control innate hyperinflammation
Endotoxemia is caused by excessive inflammation, but the immune system has various mechanisms to avoid collateral organ damage in endotoxemia. A handful of reports have shown that innate immune responses are suppressed by the adaptive immune system. However, the molecular mechanism by which adaptive...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986140/ https://ncbi.nlm.nih.gov/pubmed/24706909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321427111 |
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