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SHP-2 deletion in postmigratory neural crest cells results in impaired cardiac sympathetic innervation

Autonomic innervation is an essential component of cardiovascular regulation that is first established from the neural crest (NC) lineage in utero and continues developing postnatally. Although in vitro studies have indicated that SH2-containing protein tyrosine phosphatase 2 (SHP-2) is a signaling...

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Detalhes bibliográficos
Main Authors: Lajiness, Jacquelyn D., Snider, Paige, Wang, Jian, Feng, Gen-Sheng, Krenz, Maike, Conway, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986121/
https://ncbi.nlm.nih.gov/pubmed/24706815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319208111
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