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Dynamic Determination of Active-Site Reactivity in Semiquinone Photolyase by the Cofactor Photoreduction
[Image: see text] Photolyase contains a flavin cofactor in a fully reduced form as its functional state to repair ultraviolet-damaged DNA upon blue light absorption. However, after purification, the cofactor exists in its oxidized or neutral semiquinone state. Such oxidization eliminates the repair...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985926/ https://ncbi.nlm.nih.gov/pubmed/24803991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz500077s |
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