Ribonucleosides for an Artificially Expanded Genetic Information System

[Image: see text] Rearranging hydrogen bonding groups adds nucleobases to an artificially expanded genetic information system (AEGIS), pairing orthogonally to standard nucleotides. We report here a large-scale synthesis of the AEGIS nucleotide carrying 2-amino-3-nitropyridin-6-one (trivially Z) via...

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Bibliographic Details
Main Authors: Kim, Hyo-Joong, Leal, Nicole A., Hoshika, Shuichi, Benner, Steven A.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985877/
https://ncbi.nlm.nih.gov/pubmed/24597611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo402665d
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