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Engineering the Assembly of Heme Cofactors in Man-Made Proteins

[Image: see text] Timely ligation of one or more chemical cofactors at preselected locations in proteins is a critical preamble for catalysis in many natural enzymes, including the oxidoreductases and allied transport and signaling proteins. Likewise, ligation strategies must be directly addressed w...

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Главные авторы: Solomon, Lee A., Kodali, Goutham, Moser, Christopher C., Dutton, P. Leslie
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2014
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985801/
https://ncbi.nlm.nih.gov/pubmed/24495285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja411845f
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