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Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria

[Image: see text] Cationic Antimicrobial Peptides (CAMPs) represent a first line of defense against bacterial colonization. When fighting Gram-negative bacteria, CAMPs initially interact electrostatically with the negatively charged phosphate groups in lipid A and are thought to kill bacteria by dis...

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Библиографические подробности
Главные авторы: Lee, Myeongseon, Sousa, Marcelo C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2014
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985747/
https://ncbi.nlm.nih.gov/pubmed/24460375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4015677
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