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TOR Complex 2-Ypk1 signaling maintains sphingolipid homeostasis by sensing and regulating ROS accumulation

Reactive oxygen species (ROS) are produced during normal metabolism and can function as signaling molecules. ROS at elevated levels, however, can damage cells. Here we identify the conserved TORC2/Ypk1 signaling module as an important regulator of ROS in the model eukaryotic organism, S. cerevisiae....

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Bibliografische gegevens
Hoofdauteurs: Niles, Brad J., Joslin, Amelia C., Fresques, Tara, Powers, Ted
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985744/
https://ncbi.nlm.nih.gov/pubmed/24462291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.12.040
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