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Aptamer-guided gene targeting in yeast and human cells
Gene targeting is a genetic technique to modify an endogenous DNA sequence in its genomic location via homologous recombination (HR) and is useful both for functional analysis and gene therapy applications. HR is inefficient in most organisms and cell types, including mammalian cells, often limiting...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985672/ https://ncbi.nlm.nih.gov/pubmed/24500205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku101 |
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