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Aptamer-guided gene targeting in yeast and human cells

Gene targeting is a genetic technique to modify an endogenous DNA sequence in its genomic location via homologous recombination (HR) and is useful both for functional analysis and gene therapy applications. HR is inefficient in most organisms and cell types, including mammalian cells, often limiting...

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Detalhes bibliográficos
Main Authors: Ruff, Patrick, Koh, Kyung Duk, Keskin, Havva, Pai, Rekha B., Storici, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985672/
https://ncbi.nlm.nih.gov/pubmed/24500205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku101
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