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Physical constraints determine the logic of bacterial promoter architectures

Site-specific transcription factors (TFs) bind to their target sites on the DNA, where they regulate the rate at which genes are transcribed. Bacterial TFs undergo facilitated diffusion (a combination of 3D diffusion around and 1D random walk on the DNA) when searching for their target sites. Using...

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Autores principales: Ezer, Daphne, Zabet, Nicolae Radu, Adryan, Boris
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985651/
https://ncbi.nlm.nih.gov/pubmed/24476912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku078
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