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Large-scale reconstruction of 3D structures of human chromosomes from chromosomal contact data

Chromosomes are not positioned randomly within a nucleus, but instead, they adopt preferred spatial conformations to facilitate necessary long-range gene–gene interactions and regulations. Thus, obtaining the 3D shape of chromosomes of a genome is critical for understanding how the genome folds, fun...

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Hlavní autoři: Trieu, Tuan, Cheng, Jianlin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985632/
https://ncbi.nlm.nih.gov/pubmed/24465004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1411
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