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Hemangiosarcoma and its Cancer Stem Cell Sub-Population are Effectively Killed by a Toxin Targeted through Epidermal Growth Factor and Urokinase Receptors
Targeted toxins have the potential to overcome intrinsic or acquired resistance of cancer cells to conventional cytotoxic agents. Here, we hypothesized that EGFuPA-toxin, a bispecific ligand - targeted toxin (BLT) consisting of a deimmunized Pseudomonas exotoxin (PE) conjugated to epidermal growth f...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985275/ https://ncbi.nlm.nih.gov/pubmed/23553371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28187 |
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