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Tumor-infiltrating myeloid cells activate Dll4/Notch/TGF-β signaling to drive malignant progression

Myeloid cells that orchestrate malignant progression in the tumor microenvironment offer targets for a generalized strategy to attack solid tumors. Through an analysis of tumor microenvironments, we explored an experimental model of lung cancer that uncovered a network of Dll4/Notch/TGF-β1 signals t...

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Detalhes bibliográficos
Main Authors: Ohnuki, Hidetaka, Jiang, Kan, Wang, Dunrui, Salvucci, Ombretta, Kwak, Hyeongil, Sánchez-Martín, David, Maric, Dragan, Tosato, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985086/
https://ncbi.nlm.nih.gov/pubmed/24520074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3118
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