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Cholesterol Modulates the Dimer Interface of the β(2)-Adrenergic Receptor via Cholesterol Occupancy Sites
The β(2)-adrenergic receptor is an important member of the G-protein-coupled receptor (GPCR) superfamily, whose stability and function are modulated by membrane cholesterol. The recent high-resolution crystal structure of the β(2)-adrenergic receptor revealed the presence of possible cholesterol-bin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3984991/ https://ncbi.nlm.nih.gov/pubmed/24655504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.02.002 |
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