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Cholesterol Modulates the Dimer Interface of the β(2)-Adrenergic Receptor via Cholesterol Occupancy Sites

The β(2)-adrenergic receptor is an important member of the G-protein-coupled receptor (GPCR) superfamily, whose stability and function are modulated by membrane cholesterol. The recent high-resolution crystal structure of the β(2)-adrenergic receptor revealed the presence of possible cholesterol-bin...

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Hlavní autoři: Prasanna, Xavier, Chattopadhyay, Amitabha, Sengupta, Durba
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984991/
https://ncbi.nlm.nih.gov/pubmed/24655504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.02.002
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