Regulation of CDKN2B expression by interaction of Arnt with Miz-1 - a basis for functional integration between the HIF and Myc gene regulatory pathways

BACKGROUND: Hypoxia- and Myc-dependent transcriptional regulatory pathways are frequently deregulated in cancer cells. These pathways converge in many cellular responses, but the underlying molecular mechanisms are unclear. METHODS: The ability of Miz-1 and Arnt to interact was identified in a yeast...

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Détails bibliographiques
Auteurs principaux: Aesoy, Reidun, Gradin, Katarina, Aasrud, Kathrine S, Hoivik, Erling A, Ruas, Jorge L, Poellinger, Lorenz, Bakke, Marit
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984710/
https://ncbi.nlm.nih.gov/pubmed/24618291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-54
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